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These 4 outcomes are separated by 3 thresholds: i) invasion threshold, ii) persistence threshold, and iii) host extinction threshold.
There were also significant decreases in the migration, the Matrigel invasion and the collagen I invasion.
In the si FSCN1-transfected cells, the inhibition of Matrigel invasion and collagen I invasion paralleled that of the migration.
Collectively, these results indicate a critical requirement of MT1, and not other MMPs, for collagen I invasion.
This might explain why MMP inhibition has had, at best, only a modest influence on Matrigel penetration as compared to collagen I invasion.
We conclude that MT1 is necessary for collagen I invasion by ovarian cancer cells, and that its requisite activity is the promotion of matrix degradation, with no impact on cell motility.
Similar(48)
This dissemination may take two forms: (i) localized invasion throughout the tissue and into the adnexa or (ii) metastatic dissemination [ 64].
This HER-I-mediated invasion of LYP1 by CAN1 leads to initiation of DNA synthesis on chromosome XIV, which may then be subjected to dissociation and re-invasion cycles as previously described [6].
A type I collagen invasion assay was performed to determine whether JS-K may inhibit the invasiveness of breast cancer cells across the bone matrix.
During Xerxes I's invasion of Greece in 480 bc, the Cypriot kings, like the Ionians, contributed naval contingents to his forces.
I mean invasion like emotional abuse, rage, addiction, sexual abuse, bullying.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com