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Exact(1)
Since (i) influx of Ca2+ could act upstream of the O3-induced activation of anion channels (Figure 4E) and (ii) H2O2 was shown to activate PM Ca2+ channels [49] and increase [Ca2+]cyt in our model [25], we further tested whether H2O2 could activate anion channels.
Similar(59)
Possible origins for the 6-OH-BDE-47 induced increase in [Ca2+] i are influx of extracellular Ca2+ or release from intracellular Ca2+ stores.
The important silencing parameters are the RISC activation rate (b1), the RISC cleavage rate (b2), the number of Dicers (D i ), the influx of free RISC (i), and the siRNA production rate (c d and c s ).
Is the influx of leukocytes in asthma or sarcoidosis functional or just a spill over?
In contrast, infection with Chlamydia muridarum 28, Candida albicans 29, and prolonged sterile inflammation 30 cause IFN I-dependent influx of PMNs and iMs leading to exacerbated inflammation, similar to TB described here.
A test was performed to evaluate the robustness of the macro-parameter estimation of the [18F]FCho influx (i.e. K i) (vide supra) using these three models, i.e. 3C2i, 2C1i, and the Patlak plot.
Two models have been suggested, i.e., influx hindrance and efflux enhancement.
Values of K i, the [18F]FDOPA influx constant, were significantly lower for the ipsilateral striatum compared to the contralateral side.
Under the conditions of zero-trans influx (i.e., [S]R ≈ 0 and [S]L ≫ K M,influx), V influx equals to k' (≈k 4, assuming k 2, k 3 ≫ k 4).
Tumor rate constant of [11C]erlotinib influx, i.e., K1, showed a trend towards positive correlation with TBF(E−) and TBF(E+); however, this was not statistically significant (r s = 0.714, P = 0.058 and r s = 0.405, P = 0.327, respectively, see Fig. 3c) (see Additional file 1: Table S4 for detailed results).
The same agents were also tested in the absence of capsaicin, where none of them induced Ca2+ influx, i.e., they did not activate the vanilloid receptor.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com