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I divide this into two parts: (i) infant mortality at birth; and, (ii) having your child living past the age of 5.
We obtained the following mortality data of those 138 countries: (i) Infant mortality rate (IMR), (ii) neonatal mortality rate (NMR), (iii) under-five mortality rate (U5MR), (iv) female U5MR, (v) rural U5MR, (vi) U5MR due to HIV/AIDS, (vii) U5MR due to pneumonia and (viii) U5MR due to diarrhoea, from the official global database, WHO statistical Information system (WHOSIS) [ 18].
As a capacity building and the first stage towards a more complex regimen, the safety and immunogenicity of MVA.HIVA vaccine alone is under evaluation in two phase I infant vaccine clinical trials in sub-Saharan Africa [12].
By publication time, this I infant was 5 years old with normal renal and cognitive development for her age.
Infant development at 12 months of age was measured by the Mullen Scales of Early Learning (n = 231) and the Short Form: Level I (infant) of the MacArthur Bates Communicative Development Indices (n = 218).
In parallel with the phase IIb/III infant studies, a large study was performed in adolescents, who represent a second major target group for meningococcal vaccination.
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Exclusion criteria: (i) infants with congenital abnormalities known to affect neurodevelopment and (ii) infants with non-English speaking parents.
Exclusion criteria: (i) infants with congenital abnormalities known to affect neurodevelopment (ii) infants requiring admission to neonatal intensive or special care nursery and (iii) infants with non-English speaking parents.
Group I: infants were directly referred for complete audiological evaluation.
Advances in neonatal critical care have dramatically improved survival rates from these injuries, but approx. 50% of H/I infants would subsequently suffer neurologic sequelae.
Birth weight standard deviation score (z-score) and the prevalence of large- and small-for-gestational-age infants (i.e. infant birth weight >90th or < 10th centile, adjusted for sex and gestational age 22) were also recorded.
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