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Our objective was to assess how the diagnosis and treatment of mucopolysaccharidosis I (MPS I) have changed over time.
Clearly, the definition of stage I have changed over time and stage migration phenomena are relevant when discussing results of RT alone from older series.
This report looks at how diagnosis and disease-specific treatment of MPS I have changed over time by analyzing aggregate data from nearly 900 patients enrolled in the MPS I Registry.
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Others have changed over time as well.
I've changed over the years on that.
If I've changed over the last 20 years, then so have hostels.
In addition, I had changed over time — I had become so much more familiar with the sadness, insecurity within me and as a result I was more ready than ever to feel the emotional pain of other people.
But I don't know that my ideas – there are some points of view I guess that I've changed over the years, but I'm pretty much the same person.
When asked about his political philosophy, he replied, "There are some points of view I guess that I've changed over the years, but I'm pretty much the same person".
My sense of Scottishness varies with the company I'm in and it has changed over the years.
I suppose they have changed over time.
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