Sentence examples for I escalation from inspiring English sources

In the 15 patients included in the phase I escalation testing, no serious toxicity was observed at levels 1 and 2. Haematologic toxicity was, in general, acceptable at the level 3 dose (125 mg m−2 of irinotecan and 135 mg m−2 of paclitaxel).

RTOG 9311 [ 10] was a phase I ∼II dose-escalation study for patients with inoperable NSCLC treated with 3D-CRT.

Fig. 1 Immuno-PET signal components in a phase I dose escalation study.

Thirty-two patients were enrolled: 12 in the phase I dose escalation phase and an additional 20 in phase II to gain additional experience with the regimen.

OSI-930, a dual c-Kit and KDR tyrosine kinase inhibitor, is reported to have undergone a Phase I dose escalation study in patients with advanced solid tumors.

We present a Phase I dose escalation trial design based on a modified continual reassessment method that allows for sharing of information between populations.

Preclinical studies of the type described in this report must be combined with surrogate imaging agents to establish safe starting activity levels for phase I dose escalation trials.

5. I think "escalation" is the wrong word because it denotes a primarily military solution.

A phase I dose escalation trial of TPA has been performed in patients with relapsed or refractory malignancies and the tolerated dose has been established [18].

A Phase I dose escalation study was performed.

Presently, Quark Pharmaceuticals has enrolled patients for phase I/II dose escalation and safety studies.