Exact(52)
Factor I has been used in the treatment of factor I deficiency [87, 88].
Several patients who suffer from factor I deficiency have been diagnosed [87].
The structural NDUFS1, NDUFS2, NDUFV1, and NDUFS4 genes are mutational hot spot genes for isolated complex I deficiency.
The effect of agents commonly used in the therapy of mitochondrial complex I deficiency was examined in fibroblasts from a patient.
However, the authors used anti-CD19-CAR particles to transfect the K562 cell line (the first human immortalized myelogenous leukemia line with MHC class I deficiency).
Administration of factor I to one of the patients with factor I deficiency normalized C3b levels within few minutes [87, 88].
Similar(8)
Furthermore, sexual dimorphic gene expression, the effect of liver-derived IGF-I deficiency, as well as ghrelin secretion were studied.
Insulin-like growth factor-I (IGF-I) deficiency may be involved in cognitive deficits seen with aging and in neurodegenerative diseases such as Alzheimer's disease (AD).
Untreated patients with congenital growth hormone deficiency (GHD) and IGF-I deficiency are characterized not only by dwarfism but also by acromicria and organomicria, such as the heart.
The aim of the current study was to investigate the impact of long-term IGF-I deficiency on flow-mediated dilation (FMD) in 11 non-IGF-I-treated LS adults with long-term IGF-I deficiency who on stress echocardiography were found to have reduced cardiac dimensions and output, but normal left ventricular (LV) ejection fraction at rest and LV contractile reserve following stress.
A complex-I deficiency was evident in patients harboring A4136G and T11916A variants (Table 2).
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