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More recently, Garlid has proposed a more direct mechanistic pathway to link MitoKATP channel opening with MPTP inhibition through PKG, mitochondrial PKC-ε, the MitoKATP channel, matrix alkalinization, superoxide and hydrogen peroxide production from complex I (Costa et al., 2005; 2006; Jaburek et al., 2006; Costa and Garlid, 2008).
Therefore, iodine is rapidly absorbed by the thyroid gland, including I (Costa et al. 1991; Fisher and Klein 1981; Zanzonico 1997).
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