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These candidate clusters are then filtered to remove (i) clusters having less than four proteins and (ii) clusters having a large diameter.
We compared (i) clusters 1 ('Irano-Caucasian') and 3 ('North Mediterranean Basin'), (ii) clusters 1 and 4 ('South Mediterranean Basin'), and (iii) clusters 3 and 4. For each comparison, 50000 simulations were run using the infinite allele model for markers.
Histology of the mass revealed two hallmarks: (i) clusters of large lipid-laden macrophages with foamy cytoplasm (xanthoma cell seen in Figure 4, white arrow and black arrowheads) and (ii) multinucleated giant cells.
This time, our objective is to independently detect (i) clusters of x2, f1 x2 and s1 sites, and (ii) clusters of x1, f2 x1 and s2 sites within the alignment (as candidates of introgression blocks).
An analysis using Fdist2 software was conducted on three comparisons of these three main clusters: (i) clusters 1 ('Irano-Caucasian') and 3 ('North Mediterranean Basin'), (ii) clusters 1 and 4 ('South Mediterranean Basin'), and (iii) clusters 3 and 4. The F ST calculated by Fdist2 between clusters 1 and 3 was 0.105.
Three clusters showed significant enrichment in at least one functional process (Bonferroni-corrected HTable 0.05; Table S4): (i) Clusters 1 and 3, which represent genes showing down-regulation with age and lower expression in females, were enriched in neuron-related functions, such as neurotransmitter secretion and neural development.
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CSP i,s : cluster head selection priority of S i in sector s.
It is (i) cluster-based, (ii) propagation-based, but stochastic, (iii) double-directional, (iv) time-variant. .
Table 1 Nomenclature Notation Description Φ i Cluster with the i th node as the cluster head.
The application of this method allows the simultaneous measurement of (i) cluster solid concentrations, (ii) individual cluster slip velocities and (iii) individual cluster sizes.
(i) Clustering individuals from an outcrossing species into putative populations (represented approximately as panmictic populations).
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