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Elevated systolic and/or diastolic [Ca2+] i can activate intracellular cascades leading to hypertrophic growth.
"I hope that I can activate everybody to get off their hands and feet and go out into the communities and push helping each other," he said, per NFL.com.
"We're also seeing a select number of advanced buyers or brands that have taken their digital best practices and say, 'Hey, I can activate my first-party data across the internet... how can I do that on television?' We're looking at how we can solve those problems".
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IGF-I can activate the RAF-MEK-ERK cascade in the otic epithelium, and C-RAF is essential for otic vesicle proliferation and morphogenesis [15].
IGF-I can activate the RAF-MEK-ERK cascade in explanted otic vesicles and by blocking RAF kinases with Sorafenib, we show that RAF activity is essential for cell proliferation.
It is known that MAVS is a potent inducer of IFN-I responses and that IFN-I can activate host apoptotic responses, therefore it was important to determine whether the cell death responses observed in the current study were a consequence of IFN-I secretion.
It was found that exogenous IGF-I can activate caspases 3/7, 8 and 9 in all four cell lines, and that the activation is via the IGF-I receptor.
Also, we do not know whether IGF-I is acting here independent of 17β-estradiol to stimulate ER-α, but results from cell culture studies have shown that IGF-I can activate ER-α in the complete absence of estrogen [ 53, 54, 60] as well as acting with 17β-estradiol [ 53, 56] to stimulate ER-α.
In some cell lines, it can activate transcription [31].
These results indicate that (i) VvMYB5b can activate transcription in yeast and (ii) that the R69L substitution significantly reduces VvMYB5b transcriptional activities.
Thus, this study was designed to determine whether anti-HLA class I antibodies can activate AECs to produce growth factors and to undergo apoptosis.
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