We focus here on three of the sources of confounding that can substantially complicate the identification and genotyping of variants from NGS data: (i) alignment artefacts around small insertions deletions (indels), (ii) PCR artefacts from library preparation and (iii) error profile of reads.
Although there is also evidence that the degradation of other RNA occurs, it has been difficult to distinguish between (i) experimental artefacts, (ii) natural RNAs that are degradation products, and (iii) natural sRNAs that have a functional role.
I thought "Artefacts" could not be just about anachronism.
The effectiveness of current software development strategies, such as Model-Driven Development (MDD), depends largely on the quality of their primary artefacts, i.e. software models.
The restricted size (50 mm) of the cubes used on the LegIT means they cannot reflect internal processes present in masonry stone and are more comparable to sculptural stone i.e. artefacts or architectural details.
Artefacts (i.e. non informative alignments due to the high percentage of identity but very low coverage of the sequence) and nested genes constituted a minority of this class.
The empirical fndings from this project show it was efec-tive to adopt and use the ICF as a subtext or framework to structure previously desired cultural artefacts i.e. a multidisciplinary transfer of care report.
Originating in cultural-historical psychology, as initiated by Vygotsky, Leont'ev and Luria, and expanded by Engeström (Engeström 2001; Engeström et al. 1999; Vygotsky 1978), AT offers a framework for describing interactions of people, tools (i.e. artefacts) and rules within complex systems.
Hence, the percentage change of the volume measured with the 175-HU threshold underestimates the change in actual artefacts (i.e. the volume measured with the 175-HU threshold without the volume of radiopaque components with densities over 800 HU) [ 12].
Similar long-branch artefacts, I suggest, account for the relative positions of groups I-III on the tree.
