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Finally, a constant gap penalty C f is applied to fusion transitions in which t i aligns to G/ G′ and t j aligns to S/ S′.
If the upstream end of node v i aligns to the downstream end of node v j, the edge in the graph would be e = (v i, v j ).
For example, transcript I aligns identically to the EST predicted gene structure.
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Intuitively, new family members should (i) align well and (ii) show the same secondary structure.
The number of reads x i aligned to genomic position i is an unbiased estimate of RNA abundance.
The algorithm then iterates the steps of (i) aligning the graphs using the estimated parameters and (ii) estimating the maximum likelihood parameters until convergence.
"Everything I do I align with charity," Ms. Lanfrank said.
How do I align text using the Rich Content Editor?
"If I align with a brand, it needs to align with my values".
Later I aligned myself with critics who saw Amanda as the center of things.
But if I design a knife right now, I align everybody around that knife.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com