Sentence examples for I activation from inspiring English sources

In this paper, activity of the catalyst is discussed from the following points; (i) activation by restructuring, (ii) activation by forming active sites and reactive intermediates, (iii) site dependent turnover frequency, and (iv) role of promoting materials.

In i), activation level of cis-acting sites is discretized (beyond on/off) based on transcription factor concentration (see above).

This WIN55212-2 reffectl effecoulduld be due to (i) activation of cannabinoid CB2 receptor; (ii) activation of non-CB1, non-CB2 receptors.

These findings indicate that: (i) activation of the AKT pathway, and (ii) upregulation of MCL-1 and BCL-xL are key facets in mediating ABT-199-resistance.

We showed that Khz-cp induces mitochondrion-mediated apoptosis preferentially in transformed cells, and the signaling pathway of Khz-cp-induced apoptosis involves an increase in [Ca2+] i, activation of P38, and ROS generation through NADPH oxidase and mitochondria.

Therefore, there may well be pSS patients with local IFN type I activation in the glands but lacking systemic IFN type I activity, similar to NOD mice.

Two longitudinal studies failed to show ability of IFN-I activation to parallel acute changes of disease activity [ 6, 7].

The attachment of the 5′-triphosphate group to the passenger strand of a siRNA construct did not induce a significant improvement in the in vitro RNAi-mediated gene silencing activity nor a strong specific in vitro RIG-I activation.

RIG-I activation is tightly regulated by post-translational modifications, such as polyubiquitination and phosphorylation.

Binding to ATP through K270 of the superfamily II (SF2) domain is important for RIG-I activation.

Besides, RIG-I activation is accurately orchestrated by the post-translational modifications, such as polyubiquitination, phosphorylation, and deacetylation.