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Next, we sought to humanize mAb 85RF45.1, introducing as much human sequence as possible while retaining sequences that preserve the binding characteristics of the antibody.
MGF files were searched using the human sequence library.
It is not important that we didn't actually finish the human sequence yet.
The human sequence may be used to facilitate construction of other mammalian genome maps using the same strategy.
Zook, J.M. et al. Integrating human sequence data sets provides a resource of benchmark SNP and indel genotype calls.
Using the databases, they can see if the human sequence closely resembles, say, a yeast gene with a known function.
Several recombinant systems have been developed for production of human sequence collagens.
Therefore, we generated antibodies against these potential 20 new amino acids of the human sequence.
This problem varies from species to species, and has been much discussed for human sequence analyses.
The mouse genome was of great help to Celera in annotating its human sequence and pinpointing the location of human genes.
At a separate conference to discuss the project, Dr. Gilbert declares, The total human sequence is the grail of human genetics.
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