This highly simplistic assumption, substantiated by an enormous amount of evidence both from the point of view of the ribosome and that of the mitochondrion, will serve as a first approximation toward the analysis of the pathogenic potential of mt-rRNA mutations.
For example, simplified, monodimensional hypotheses on land-use intensification, for example, on the interrelationship between agricultural intensification and area demand, though initially highly intuitive, cannot be substantiated when evaluated against empirical data [ 18,19].
The suspicion of a functional defect has to be substantiated by highly specialized tests, which are expensive and performed in few laboratories, and is thus not always easily accessible in every country.
On the basis of these results it can be concluded that 6T molecules form a quasi-closed layer after the deposition of 1 ML, which further substantiates the highly homogeneous green fluorescence of p-6P nanofibers.
This is substantiated by the occurrence of highly lignified cells in the exocarp of A. gregorii, as well (Bleechmore 2002).
This presupposition is substantiated by our finding of highly enhanced TCF-mediated transcriptional activity in the cell lines JROECL19 and JROECL33, both with nuclear β-catenin expression.
She substantiates her argument with the highly controversial theories of Ray Blanchard, a retired professor of psychiatry at the University of Toronto, and the related work of J. Michael Bailey, a psychology professor at Northwestern University.
Hospitals are nowadays more and more confronted with budget cuts and accountable to substantiate their costs spent on highly specialised, top-referral care.
However, in order to substantiate these preliminary results, many highly relevant to disease prevention and potentially with significant socio-economical health benefits, multi-centre epidemiological studies involving hundreds or thousands of subjects over prolonged periods of time would be necessary.
From the crystallographic study using the edge-to-edge matching model, electron backscatter diffraction and transmission electron microscopy, it is substantiated that the Al3Zr particles are highly potent nucleants for Al.
