Sentence examples for Highly substantial from inspiring English sources

PREEMPT supports the efficacy and tolerability of onabotulinumtoxinA for the prophylaxis of headache in adults with CM.[1] These data demonstrate that onabotulinumtoxinA treatment results in a significant 75% reduction in multiple headache symptom measures and highly substantial efficacy for a subpopulation of patients studied.

However, once this volume is reached the effects were highly substantial.

Regarding CSME, κ was 0.73 (SE = 0.061) for grader 1 and 0.77 (SE = 0.056) for grader 2, which means a highly substantial agreement between the imaging methods.

Influence of the RS on the change rate was highly substantial if patients with initial recommendation for chemotherapy or hormonal therapy were considered separately (P < 0.001 for both).

κ for grader 1 was 0.792 (SE = 0.039) and 0.774 (SE = 0.039) for grader 2, indicating a highly substantial agreement between the imaging methods.

A highly substantial agreement between both Optomap DR and CSME grading and ETDRS 7-field photography existed with κ = 0.79 for DR and 0.73 for CSME for grader 1, and κ = 0.77 (DR) and 0.77 (CSME) for grader 2. Determination of CSME and grading of DR level from Optomap Panoramic 200 nonmydriatic images show a positive correlation with mydriatic ETDRS 7-field stereo photography.

Furthermore, for this subgroup both the fixed effect and random effects estimates suggest a highly Significant and substantial detrimental effect of neoadjuvant chemotherapy.

This notion was reinforced by the substantial, highly significant deficit of nonsense mutations in both EST collections compared to the neutral expectation (Table 1).

There were substantial highly significant raised risks in Indian ethnic migrants for cancers of the mouth and pharynx, gall bladder, and liver in each sex, larynx and thyroid in males, and oesophagus in females.

The v-fos FBJ murine osteosarcoma viral oncogene homolog gene (FOS) displayed an expression profile that showed highly significant and substantial decreases – again, in a coordinated fashion – between the N'Dama and Boran groups, which were particularly apparent from 21 dpi onwards relative to pre-infection levels.

The overall canonical correlation was substantial and highly significant (canonical R = 0.98, p < 0.01).