Furthermore, by this method any order derivatives of the solution can be highly approximated on the 'singular' parts, which are difficult to obtain in other numerical methods.
The activated IRAK1/TRAF6 then induces IL-8 production (Figure 1, red arrow, a highly approximated estimate from the multiple-step activation through the MAPK and IKK-NF-kappaB cascades, transcription, transcript stability, translation and post-translational processing).
This occasioned the first balloon drop in the renovated Tully Hall, each balloon a sea of blue bearing highly approximate green continents.
A highly approximate eigensolution are generated by the proposed method, which is combined the newly added DOF (Degrees of Freedom) condensation, ICMO strategy (Independent and Coupling Mass Orthogonalization) with the Rayleigh Ritz analysis.
The obtained results can be used to highly approximate the derivatives for the solution of Laplace's equation by the finite difference method, in some version of domain decomposition methods, in composite grid methods, and in the combined methods for solving Laplace's boundary value problems on polygons (see [10 13]).
And evidently, it seems that more than 95% of the cosmos is made up of dark matter and dark energy, two highly approximate ideas we really don't understand one bit.
Although statistical-thermodynamic models offer quantitative estimation of the effect of crowding on protein stability, descriptions of the potential of mean force acting between a rigid crowding particle and a flexible non-native protein conformation remain highly approximate, and the estimates of the magnitude of crowding effects on conformational equilibria vary widely [15], [21].
The purpose of these estimates is just to give an idea of the time scale involved because they are certainly highly approximate.
By providing even a highly approximate estimate of unmeasured confounding in a few simple steps, the ACCE Method could help more accurately indicate which prominent "signals" (either in effectiveness or safety) observed during the screening of large datasets appear to be less confounded (and thus are a particular priority for further investigation).
Only the less constrained terminal regions gave significant chemical shift effects in CEST experiments, therefore, we could not obtain detailed structural data on the low-populated hidden state and can only provide a highly approximate structural model based solely on moderately informative N chemical shifts (see the Supporting Information, Figure S47 and Table S5).
The details discussed below may not prove as important if the method is ultimately determined to provide only general, highly-approximate qualitative estimates of residual confounding.
