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The study was designed to reveal the impact of pRT on normal brain tissue metabolism, which may potentially help in delineating the target volumes for reirradiated patients.
Mullins et al. (2009) showed that in the case of large fluid conditional variations and compartmentalization, DFA can be used as a tool to help in delineating these variations in a cost-effective manner.
Genome-wide association studies and protein biomarkers may help in delineating underlying biological differences between the classes.
This will help in delineating their potential function.
Furthermore, the understanding of the biological function of MIC-1 in prostate may help in delineating its role in prostatic physiology and pathobiology.
Furthermore, our study will help in delineating specific disease mechanisms that will pave the way for the identification of relevant therapeutic targets that influence detrimental changes in chondrocyte phenotype.
This information could help in delineating the relevant antigens represented in various PPDs, which could further lead to development of a lesser complex and better defined skin test antigen with a higher specificity and sensitivity.
Comparison of these structures is expected to assist the design of inhibitors against specific GGTs and also help in delineating features responsible for substrate specificity and protein stability, thus providing leads to engineering GGT proteins with desirable biotechnological properties.
In the future, a panel of biomarkers might help in delineating distinct populations of patients with discrete pathologies - a prerequisite to enable the targeted application of specific biologically rational therapies.
The detailed analysis of these sites would help in delineating the amino acids that are responsible for differences in biochemical features and structural stability in GGTs of these clades.
Further biochemical characterization of the putative divergent sites identified by our study could help in delineating the role of these amino acids in imparting thermal/pH stability and those responsible for differences in enzyme kinetics and substrate specificities.
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