Sentence examples for Hallmark of disease from inspiring English sources

This, in turn, appears to trigger the fibrillization of the inclusion bodies that are a hallmark of disease.

Accurate and reliable estimates of kidney and cyst volume, the hallmark of disease progression in ADPKD are now available.

Moreover, in the majority of those with ALS and FTD, the pathologic hallmark of disease is the cytoplasmic deposition of the nuclear RNA binding protein TDP4317, implying a common mechanism underlying these clinically-overlapping neurodegenerative disorders.

With the aim of identifying a worsening factor in MOH, rather than the detection of a specific risk factor for the development of the disease, we investigated whether the presence of a functional BDNF polymorphism might determine clinical differences within a group of 90 MOH patients, particularly in monthly drug consumption, that is the hallmark of disease.

Aim of this study is to confirm our hypothesis that allele A of the examined BDNF polymorphism interfere with MOH, seeking for clinical and psychiatric differences between the two groups, mainly in the monthly drug consumption, that is both the clinical hallmark of disease, and the feature closest to abuse disorder.

Finally, reduced levels of Bdnf promoter transcripts are a hallmark of disease progression in Huntington's disease (Zuccato et al., 2001).

Altered glycolysis is a hallmark of diseases including diabetes and cancer.

CRISPR-Gold was also able to reduce tissue fibrosis – the hallmark of diseases where muscles do not function properly – and enhanced strength and agility in mice with Duchenne muscular dystrophy.

Importantly, chronic NET formation, or NETosis, is a hallmark of diseases including rheumatoid arthritis, lupus, and numerous cancers.

Thus, the normal condition of an organism must be understood in order to recognize the hallmarks of disease.

The idea that the hallmarks of disease could be detected through computational analysis has been alluring to engineers.