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A random sample of 32 patients was taken from patients who had enroled between September and November 2007.
In February 2004, when we had enroled half of the planned number of patients (245), we performed a planned interim analysis for safety monitoring and potential sample size recalculation based on the distribution of pathological stage in study population.
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Currently, the lymphadenectomy in ovarian neoplasm international RCT, sponsored by the onco-gynaecologic German group AGO, that investigates the role of systematic lymphadenectomy at primary surgery in advanced stage IIB IV ovarian cancer, completed debulked, has enroled almost 650 women and the results are awaited.
Analysis of clinical outcomes was done by Sylvester Cancer Centre following closure of the study by the sponsor after 39 patients had been enroled and treated.
Regarding prior diagnosis and treatment, 25 patients (32%) presented with locally advanced pancreatic carcinoma, 47 (60%) presented with metastases, and 6 (8%) had been enroled following recurrence after surgery.
She home-schooled her own children, but by law had to enrol her foster children into local public schools.
Each GP had to enrol up to 4 consecutive patients with acute LBP.
However only 13.5percentnt of children estimated to be living with HIV have been enroled in treatment.
A pivotal study of catumaxomab in ovarian cancer patients with malignant ascites has already enroled more than 250 patients.
These managers, in turn, had to enrol individual groups within the organisation so that established networks could be re-organised.
However, 25 patients have been enroled as suggested by the entropy-based approach to sample size in translational clinical trials (Piantadosi, 2005b).
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