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This precision was determined by Monte Carlo simulation in granddaughter designs.
The aim of this study was to develop the linear haplotype sharing transmission disequilibrium test (LHS-TDT) method and combine this method with the simple regression method to estimate the precision of QTL positions in granddaughter designs.
Therefore, for populations similar to those population simulated in this study, the LHS-TDT was better than the simple regression method and the combined method for precision of estimated QTL position in granddaughter designs.
Such information can only be detected by pedigree analysis, such as daughter or granddaughter designs.
Empirical power was determined by Monte Carlo simulation in granddaughter designs.
The first two requirements for concordance can be analyzed directly from daughter or granddaughter designs results.
Similar(50)
Ten grandsire families were used in a granddaughter design.
The mapping population consisted of 12 bulls and their 491 sons in a granddaughter design.
A statistical model was applied to a granddaughter design to analyze 16 German Holstein families.
The mapping population consisted of 10 sires and their 417 sons in a granddaughter design.
Genome coverage was estimated to be 2713.5 cM (90%) for 406 markers using a granddaughter design.
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