Sentence examples similar to Grade decrement from inspiring English sources
Within the various increments and decrements in GRADE, several implicit judgments are necessary.
In NSCLC, decrements for AE vary from 0.35 for severe AE (such as dyspnoea grade ≥3)[ 12], to decrements of 0.03 for rash, to a range from 0.09 to 0.27 for neutropenia [ 14- 16].
There were no toxicities greater than grade 1 or ejection fraction decrements below normal.
Hence the addition of RBI Grade 81 to clay soil a drastic decrement in PI and consequently turning the soil behaviour into non-plastic (Fig. 3).
In cases of grade 3/4 gastrointestinal toxicity, the UFT dosage was decremented by 100 mg day−1.
Hair loss had the smallest utility decrement in both countries (–0.03) and hospitalisation for grade III /IV toxicity had the greatest utility decrement (−0.13 (United Kingdom) vs −0.20 (Australia)).
Among the toxicity states, grade I/II nausea and nausea/vomiting had the smallest utility decrements (both were -0.05), and grade III/IV pneumonia had the greatest decrement (-0.20).
Of note, afatinib-treated patients were permitted to dose-escalate from the initial 40 mg dose to 50 mg/day after the first 21-day treatment cycle if no drug-related AEs higher than grade 1 were experienced, while dose reductions in 10 mg decrements to a minimum final dose of 20 mg were recommended for patients experiencing drug-related grade 3 or selected prolonged grade 2 AEs [ 66, 67].
