When generated excessively or when antioxidant function is disturbed, ROS can be cytotoxic through the oxidation of biomolecules (e.g., membranes, enzymes, carbohydrates, DNA).
However, the endogenous mechanisms involved in free radical scavenging in the living cell sometimes become unbalanced and may be inadequate to neutralize the free radicals generated excessively.
When a pig is stressed, it can enter a hypermetabolic state that generates excessively high temperatures and low pH's.
A second factor, individual power needs (especially by the chief executive) tend to generate excessively centralized structures.
Worse, it is negatively affecting our communities and taxpayers because justice denied today generates excessively high costs in undoing the damage tomorrow.
However, as Bohannon et al. have noted as collision problem, it often generates excessively large equivalence sets by applying repeated merges with multiple rules.
This consequently generates excessively strong atmospheric waves (Tsuda and Hocke, [2004]), some of which can propagate upward to the dynamo regions to disturb the neutral wind there and hence the electric field and currents.
Because this positioning generated an excessively positive static fluid head, the headspace pressure in this reservoir was reduced below atmospheric pressure through a pneumatic pressure/vacuum regulator (Fairchild, Model 16) and monitored by a differential capacitance manometer (MKS Baratron, Model 698A, 1000 mbar full-scale with 0.001 mbar resolution).
Mr. Ashcroft's steps will generate more excessively long prison sentences -- an approach half the states now see as costly and unjust.
Because this level of resolution unnecessarily generates an excessively large dataset, an in-house written MatLab code was utilized to average across every 5 data points, giving a new resolution of 0.004 ppm and 2645 data points per sample.
Installed correctly, and with tight connections, aluminum wire is not excessively dangerous, but when connections are made to copper wires, an electrolytic reaction may occur, causing increased resistance in the connection which will generate excessive heat.
