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A number of studies indicated that APs of a gene have different tissue specificity [18], [19], developmental activity [20] and/or transcription activity [21], and generate transcripts with different 5' untranslated regions (5'UTR) or open reading frames (ORF) [22].
The frequent use of iTSSs by RNAPII thus does not generally result in the production of truncated proteins and tends to generate transcripts that are sensitive to NMD. 10.7554/eLife.06722.020 Figure 8. Distribution of in-frame vs out-of-frame ATG codons and methionines for genes with or without transcription start sites downstream of annotated ATGs (iTSSs).
We also generate transcripts and store those transcripts in physical and digital formats.
I regrettably don't have the time or resources to generate transcripts of my talks.
Several weeks ago Adobe added voice recognition technology developed by Autonomy, a British firm, to its Creative Suite software, allowing it to generate transcripts of video and audio recordings with a high degree of accuracy.
Furthermore, it is likely that many phase shifting splice events generate transcripts which are degraded via nonsense-mediated decay [18].
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Annotated sequences provide genomic bounds to which one can either map the sequence reads directly or within which one can sum all the mapped reads to generate transcript counts.
It remains unknown whether operonic genes generate transcript isoforms in a similar manner as non-operonic genes do, the expression of which is less likely limited by their positions and relationships with surrounding genes.
Gene alleles that generate transcript structure variations are especially interesting since the variations at CDS regions cause more significant changes in protein sequence, structure and function than SNP alone.
There are multiple mechanisms to generate transcript isoforms, which includes five major categories [ 44].
MITE insertions are highly polymorphic among grapevine cultivars, which frequently generate transcript variability.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com