Gain domain of

USAGE SUMMARY

The phrase "Gain domain of" is not correct in standard written English.
It seems to be a misphrasing and does not convey a clear meaning. Example: "To succeed in this field, you must gain domain of the necessary skills."

⚠ May contain grammatical issues

Science

Human-verified examples from authoritative sources

Exact Expressions

7 human-written examples

In addition, the GAIN domain of GPR56 (a different cell-adhesion GPCR, mutations of which cause bilateral frontoparietal polymicrogyria (BFPP); Piao et al, 2004) is sufficient for autoproteolysis, suggesting that the GAIN domain mediates autoproteolysis in other cell-adhesion GPCRs as well.

EMBO Journal

Almost all ADPKD mutations in the GAIN domain of PKD1 abolished autoproteolysis, either by directly interfering with catalysis or by altering their membrane localization (presumably, by impairing folding), indicating an essential role for the GAIN domain.

EMBO Journal

The GAIN domain of rat CL1 (residues Thr533 Ile849) was cloned into a pCMV5 vector and fused to Ig (26 kDa) at the C-terminus and carried an HA tag at the N-terminus.

EMBO Journal

The GAIN domain of mouse GPR56 (residues Q115 E395) was cloned into the pDisplay vector with N-terminal HA and C-terminal myc tags and has the PDGFR single-spanning transmembrane domain at the C-terminus.

EMBO Journal

The GAIN domain of PKD1 is a hot spot for mutations associated with ADPKD, one of the most common monogenic diseases (1 in 1000) (Qian et al, 2002; Figure 6A).

EMBO Journal

A protein fragment composed of only the GAIN domain of CL1 underwent autoproteolysis, demonstrating that the GAIN domain is not only necessary but also sufficient for autoproteolysis in CL1.

EMBO Journal

Human-verified similar examples from authoritative sources

Similar Expressions

53 human-written examples

The HormR and GAIN domains of rat CL1 (residues 460 849) and human BAI3 (residues 498 868) were cloned into the Xba1– Not1 and the BamH1– Not1 sites of the pAcGP67A vector, respectively (CL1=43 kDa plus 5 carbohydrates; BAI3=41.7 kDa plus 3 carbohydrates).

EMBO Journal

The testable model space was constrained by requiring the loss and gain domains of the utility function to be asymmetric, as symmetric functions do not predict any effect of wager size on the Type II response criterion (see Supplementary Material for a more detailed discussion of empirical forms of the utility curve).

Consciousness and Cognition

The N-terminal subdomain A of the GAIN domain is composed of six α-helices, while the C-terminal subdomain B consists of a twisted β-sandwich including 13 β-strands and 2 small α-helices.

EMBO Journal

GAIN domain is one of the few domains to mediate self-cleavage of a membrane protein.

EMBO Journal

Different from CL1, the electron density of the crystal structure of the BAI3 GAIN domain showed no evidence of cleavage, and BAI3 expressed in transfected HEK293 cells was uncleaved.

EMBO Journal

Expert writing Tips

Best practice

Instead of using "gain domain of", opt for clearer and more grammatically sound alternatives like "acquire mastery of" or "develop expertise in" to convey a sense of skill acquisition or understanding.

Common error

Avoid using "of" after "gain domain". This construction is grammatically incorrect. Instead, use phrases like "gain expertise in" or "gain mastery of" for accurate and effective communication.

Linguistic Context

The phrase "gain domain of" functions as a noun phrase aiming to express the acquisition of knowledge or skill in a particular area. However, according to Ludwig, this specific phrasing is not correct in standard written English.

Expression frequency: Uncommon

Frequent in

Science

100%

Less common in

News & Media

0%

Formal & Business

0%

Encyclopedias

0%

Ludwig's WRAP-UP

In summary, while "gain domain of" attempts to convey the concept of acquiring expertise, it is grammatically incorrect. As Ludwig AI points out, it is not correct in standard written English. Instead, it is better to use alternatives like "acquire mastery of" or "develop expertise in", which are grammatically sound and commonly used. The phrase appears infrequently, primarily in scientific contexts, but its incorrect usage undermines its effectiveness. Therefore, it's recommended to avoid "gain domain of" in favor of more accurate and widely accepted alternatives.

More alternative expressions

Phrases that express similar concepts, ordered by semantic similarity:

Acquire mastery of

Suggests a deep and comprehensive understanding or skill in a particular area.

Attain control over

Implies gaining authority or influence in a specific area.

Develop expertise in

Focuses on gradually building knowledge and skills in a field.

Cultivate proficiency in

Emphasizes the careful and sustained effort to improve skills.

Secure dominance in

Suggests achieving a leading position in a particular field.

Achieve command of

Implies reaching a high level of skill and competence.

Obtain knowledge about

Focuses on acquiring information and understanding of a subject.

Build competence in

Refers to constructing skills and capabilities in a specific area.

Foster understanding of

Suggests encouraging a deeper insight into a subject.

Enhance awareness of

Focuses on increasing perception and comprehension.

FAQs

How can I express the idea of acquiring skill in a subject other than using "gain domain of"?

Instead of "gain domain of", you can use alternatives such as "acquire mastery of", "develop expertise in", or "achieve command of" depending on the specific nuance you want to convey.

Is "gain domain of" grammatically correct?

No, "gain domain of" is not grammatically correct in standard English. It is better to use phrases like "acquire knowledge of" or "develop an understanding of" instead.

What's a more formal way to say "gain domain of"?

For a more formal tone, you can use phrases such as "cultivate proficiency in" or "attain control over" to express the idea of acquiring skill or knowledge.

What's the difference between "gain domain of" and "gain knowledge of"?

While "gain knowledge of" is a correct and commonly used phrase to mean acquiring information, "gain domain of" is not grammatically correct. It is advisable to use the former to express the idea of obtaining information about a subject.