Exact(3)
By interfering with CXCR4-CXCL12 interaction, plerixafor may also prevent internalization of CXCR4, thereby disrupting downstream signaling (for instance, in the PI3K/AKT pathway) and further sensitizing leukemic cells to therapy.
In our region birch allergen, seems to precede, and may even be driving the further sensitizing process which may be considered for further studies on therapeutic interventions.
The unadjusted data indicate the relevance of multiple allergies for the highly atopic child, whereas the adjusted data demonstrate the role of a single sensitizing allergen and its significance for the further sensitizing process during childhood.
Similar(57)
That inhibition of recombination is important for the observed sensitization is also suggested by the TK10 cells which were sensitive to gemcitabine alone, and were not further sensitized by MK-8776.
MISO given 30 min before single doses of radiation further sensitized the skin, but for 10 fractions in O2 no MISO sensitization was detected.
Thus, sensory axons are sensitive to acrylamide, but the loss of Lrsam1 does not further sensitize these axons to degeneration, whereas axons of the motor branch of the femoral nerve showed greater sensitivity to acrylamide-induced degeneration when Lrsam1 levels were reduced.
Interestingly, siRNA knockdown of MDR1 further sensitized the cytotoxic activity of paclitaxel when co-administrated with H6.
While passing through the target, each ion creates a cylindrical damage zone along its trajectory which is further sensitized by UV light exposure for 2 h.
Then the films were further sensitized by CdSe quantum dots (QDs) to serve as a photoanode for fabricating quantum dots-sensitized solar cells (QDSSCs).
YAP depletion further sensitizes human cancer cells to anti-cancer agents, such as cisplatin or the EGFR tyrosine kinase inhibitor erlotinib[118], and increased YAP/TAZ levels correlate with taxol and cisplatin resistance[100, 119, 120].
We next asked what single or combinatorial interventions would further sensitize cells to PI3K inhibition, i.e. yield an increased apoptosis propensity or decreased proliferation propensity compared to PI3K inhibition alone.
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