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Postdoc Brian, an NRSA-funded postdoc, is interested in whether the historical mechanisms by which new functions evolved represent the most functionally effective or mutationally accessible trajectories or, alternatively, whether there were many alternative routes that evolution could have taken.
Recombinant IL-6 and TGFβ1 were used at functionally effective doses to model the neuroblastoma/monocyte generated molecules to study the effects of these cytokines individually without or with lenalidomide upon NK cell activation.
The resulting organizations are constructed to be proper social actors, as much as functionally effective entities.
As a proof of concept, we have demonstrated that ribose crosslinking is cost-effective, safe and functionally effective.
These results should help to clarify the structural requirements of functionally effective ASOs in the inhibition of IL-6R.
The New World monkeys show a considerable advance over primitive primates in tactile sensitivity, but they possess less functionally effective hands in prehensile terms than Old World monkeys.
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We developed an empirical method to evaluate soils based on functionally defined effective dissolution rates.
The FokI restriction fragment length polymorphism, located in the coding region of the VDR gene, results in the production of a VDR protein that is three amino acids longer and functionally less effective [ 32].
At one time it was thought that the tumour vasculature was actually superior to that of normal tissues; this misconception arose because tumour vessels are often of large size and were, therefore, more conspicuous than the smaller, more numerous and functionally more effective blood vessels of normal tissues.
The CD4+ T cells were functionally competent, mediating effective allogeneic responses that involved polyclonal TCR Vβs.
Implantation of spring-like distractors in the treatment of sagittal craniosynostosis is a novel technique that has proven functionally and aesthetically effective in correcting skull deformities; however, final shape outcomes remain moderately unpredictable due to an incomplete understanding of the skull-distractor interaction.
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