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In order to ascertain whether individual peaks are functional, further work is needed.
Similarly, we showed by direct RNA transfection of a dicistronic transcript that the predicted IRES in the SPG4 exon 1 is not functional, further confirming the imprecision of bioinformatic approaches to predict IRES sequences and stressing the importance of adequate functional validation.
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Moreover the fact that some alleles might be non-functional further complicates the situation and obligates the differentiation of functional alleles from the non-functional ones through historical selection tests and screening of cDNA libraries.
Functional studies further demonstrate that ERBB3 on CD11c+ cells is critical to the function of antigen presenting cells (APC).
Functional housing further out requires people – residents – to tell its tale.
Functional analysis further implicates a critical role of c-Fos in initiating, but not maintaining, neuronal activity-induced chromatin opening.
Functional experiments further demonstrated that rs17740607 polymorphism decreased the HDC activity.
This functional is further generalized as | a 3 − μ a 2 2 | for some μ (real as well as complex).
These functional changes further support the idea that β4 coassembles with Slo3.
Cross-validation and functional analysis further supported the identified biomarkers.
Shared functional features further underscore the relationships between eukaryotic and prokaryotic Mutator-like transposases.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com