Despite the comfort afforded by the building, it was criticised as being "...highly improper for any Court of Justice and particularly so, for one of such importance in this Island as the House of Keys" as recorded in the Journal of the Keys in October 1817.
I consider these matters to be of such importance for this House and for its members and for the protection of free speech in our proceedings that written submissions have been made to the court on my behalf.
So another 2percentt of the genome must be doing something of such importance for each organism's survival that it has been conserved for many millennia.
They were also very worthy winners of the Fifa Fair Play Award, and the goodwill of that match against West Germany was truly remarkable for a game of such importance.
We only need to look as far as 1999's remarkable Reich Remixed album for a work of such importance, which is apt given Reich's Come Out which, I would suggest, is not only one of the greatest remixes ever, but one of the greatest works of the 20th century.
It is unfair to review a restaurant on opening night, but an event as important as the return of Doctor Who after a hiatus of 15 years (not counting the ill-fated 1996 US TV movie co-production, to which BBC executives have the same regard Stalin had for Trotsky) is of such importance to millions of fans around the world that instant judgments are required.
For an instrument of such importance, ESO had to ensure that it had the very best possible site to get the most from its investment.
On August 31 , 1687 Arnauld wrote to Hessen-Rheinfels, saying, "It would be preferable if [Leibniz] gave up, at least for a time, this sort of speculation, and applied himself to the greatest business he can have, the choice of the true religion… a decision that is of such importance for his salvation" (LA, 110).
"Given the widely recognized challenge that climate change poses to the nation and the world, this is an absurdly short amount of time for a subject of such importance," the senators wrote in their letter, addressed to top executives at Fox News, NBC, ABC, and CBS.
The results of Col1a1 indicate that the positively selected sites may have been of such importance for this protein that neighboring mutated sites may have been maintained in the population despite their propensity for causing disease.
