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For each significance threshold we then estimated a corresponding FDR using a permutation approach (see Materials and Methods).
For each significance threshold, power is estimated by the proportion of replicates for which PFAST<αFAST and PGLM meets a nominal pair-wise genome-wide significance threshold of 10−10.
Furthermore, for each significance test, the Pearson's correlation coefficientr was calculated as a measure of effect size.
All results for random reaction graphs reported here are based on 20 randomized graphs for each significance threshold.
Thus, for each significance test in this study, the critical level of significance "alpha" = 0.05/ j, where j is the number of tests.
In our study, we limited M to 100 for each significance test of γ due to the computational cost of repeating Bayesian network learning many times for each permutation.
Similar(54)
For each training data set, QTL model selection was conducted using each significance threshold for each method.
Then for each gene significance was determined using the equivalent of a one-sample t-test in limma and RankProd.
For each SNP, significance of the similarity score was assessed by 50,000 permutations.
For each comparison, significance of the more parameterized model was evaluated with a χ2 test.
For each category, significance is represented by bubble color and occupancy by bubble size.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com