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Rheumatoid arthritis (RA), psoriatic arthritis (PsA) and ankylosing spondylitis (AS) are disorders characterised by excessive production of proinflammatory cytokines, including tumour necrosis factor-α (TNF), and patients with these chronic diseases receive treatment for a protracted time.
*The recommended antibiotic, ciprofloxacin, is taken for a protracted time, perhaps 45 to 60 days.
Therefore, it could be possible to modify the design of these items such that the items detach from where they are connected to after a heavy weight is placed on them for a protracted time period.
Since laws and driver courtesy seem to mean nothing to these drivers, perhaps loss of their driving privileges for a protracted time, and fines that mean something, will help to alleviate this problem.
The origin of this practice may be associated with the belief that vaginal dryness during intercourse allows a man to maintain his erection for a protracted time [ 12].
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If we have a very protracted time when companies are strapped for cash, they may decide not to use outplacement services.
From our work, we would suggest that as it takes a protracted time for the β-catenin exon 3 mutation to have a phenotype in the small intestine, this mutation would probably be neutral (0.5) for some time.
If the infusion is given over a protracted time course (48 h) for more invasive and routinely painful procedures, patients can have a decreased risk of developing persistent postoperative pain in months that follow.
One cannot emphasize the need for repeated evaluations of the psychosocial factor over a protracted time period.
The biological basis of this link is likely to be multi-factorial including both age-associated decline in anti-oncogenic functions, such as repair of oxidative damage to DNA, timing of etiologic exposures and/or protracted time required for accumulation of a full set of oncogenic mutations [ 1, 2].
The TIPS method eliminates the need and protracted time for titering virus supernatants, and provides stable, concentrated storage of recombinant baculovirus in the form of infected cells.
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