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During the final 1 μs following re-entry the TDG molecule re-established itself 2.5 Å from the crystallographic binding position.
The RT PCR analyses clearly demonstrated significant downregulation of NS expression in G0 cells, but increased NS mRNA abundance following re-entry into cell cycle.
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At ~5.6 μs, the TDG molecule exited the protein and was released into the surrounding bulk water followed by re-entry within 100 ns.
In summary, IR induced a reversible G2/M-arrest in all DAOY cells followed by re-entry into the G1 phase.
The trip time for drill bit (i.e., the time taken to withdraw the drill stem to replace bits worn-out, followed by its re-entry into the borehole) that is required because of the abrasion and replacement of bits has a large impact on drilling time and performance.
GT apparently senses exposed patches of charged amino acids and reglucosylates the aberrant glycoproteins, which is followed by their re-entry in the calnexin/calreticulin cycle (Parodi et al. 1983; Sousa and Parodi 1995; Trombetta and Parodi 2003).
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This variable definition was chosen to account for variable patterns of participant follow-up and re-entry into the study and low rates of virologic failure at individual assessments.
Evenings were structured in three "bardos," a term that Timothy Leary had taken from "The Tibetan Book of the Dead" to describe the phases of an LSD trip: a peaceful embarkation leading to Dionysian frenzy, followed by a calm re-entry into the real world.
While high levels of cellular stress in general are associated with a p53-dependent apoptotic response, low or moderate stress may induce p53-dependent cell cycle arrest and DNA repair followed by cell cycle re-entry.
Among other components, the tumour suppressor p53 protein triggers cellular programs that lead to different fates: transient arrest followed by cell cycle re-entry upon damage repair, permanent cell cycle arrest (senescence) or, if the damage is irreparable, initiation of cell death program (apoptosis).
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com