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Furthermore, in the presence of therapeutic concentrations of erlotinib, obtained by taking a fixed oral dose of 150 mg erlotinib daily, there was still residual tumor tracer uptake.
Formation of micronuclei from multipolar mitoses had been suggested by studies on fixed oral cancer cells [22] and live Chinese hamster cells under phase contrast microscopy [23].
11 Dihydroartemisinin-piperaquine (DHA-PQ) is a promising new fixed oral combination.
Tacrolimus therapy was started at a fixed oral dose of 5 mg b.i.d. and was supported by routine TDM based on AUC0 12 h.
The fixed oral combination of dihydroartemisinin and piperaquine has demonstrated excellent cure rates in adult patients with P. falciparum malaria in Thailand (2).
In conclusion, although this was a small study, the fixed oral combination of DHA-PQ is a safe and effective treatment for pregnant women with malaria.
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Blocks of paraffin-embedded, formalin-fixed oral biopsies were obtained in accordance with Local Research Ethics Committee approval.
To delineate the clinical translatability of rapamycin in treatment of mitochondrial encephalopathy, we evaluated the drug's effects on disease evolution and mitochondrial parameters adopting treatment paradigms with fixed daily, oral doses starting at symptom onset in Ndufs4 knockout mice.
- To assess the response rate, time to progression and overall survival of the combination of metronomic cyclophosphamide and fixed dose oral everolimus.
Trials comparing fixed-dose sulfonylurea treatment administered either as monotherapy vs placebo, as an add-on to another fixed-dose oral glucose-lowering drug, or as an add-on to insulin treatment, as well as trials that compared two or more different doses of the same sulfonylurea, were included in the review.
Rivaroxaban is fixed-dose oral therapy that does not require any blood monitoring.
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