Several factors influence sexual maturation, including habitat, temperature, photoperiod, nutritional status, social interaction, pheromones, and hormones, all having role in the extensive regulatory feedback system (Taranger et al. 2010).
RLSB, as a regulator of rbcL gene expression, provides a new insight into how one component of this extensive photosynthetic regulatory system might have been modified from an original C3 "default" function to perform the same function, but in a more specialized fashion, in C4 plants.
Surprisingly, our list of experimentally defined PUM targets predicts extensive connections to the miRNA regulatory system, providing a first indication that 'cross-talk' between translational regulation through RBPs and miRNAs may be more frequent than previously appreciated [41], [42], [43].
With sequencing of complete genomes and development of comparative genomic methods, extensive analysis of a complex regulatory system in multiple genomes has become possible.
Glucose repression is a complex and intertwined regulatory system, with extensive cross-talk among pathways, feedback loops and different levels of regulation responding at different time scales.
The periaqueductal/periventricular grey contains dopaminergic neurons and has extensive reciprocal connections with the sleep-wake regulatory system [ 52].
Moreover, an extensive interaction between PUM1 and PUM2 with the miRNA regulatory system has been suggested [ 48], indicating that interactions between the RBPs and the miRNAs in translational regulation may be more frequent than previously thought.
Ms. Yellen said the new regulatory system should incorporate automatic safeguards and straightforward rules, and involve extensive international coordination.
Ms. Schapiro has extensive regulatory experience.
The regulatory system is uncertain.
