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The groups of Arthur Johnson and Carol Deutsch experimentally verified this hypothesis using FRET and/or a combination of accessibility assays, respectively [ 29, 30, 53, 59].
Experimentally verified human CM genes were obtained from three sources.
Experimentally verified piRNA target relationships were noted.
Experimentally verified targets are underlined, n.a.: no category assignment.
To experimentally verify this hypothesis, an HRgpA-induced methaemoglobin preparation (total haemoglobin concentration 16 µM and comprising 77% in the oxidised form) was incubated with HmuY (16 µM).
To experimentally verify this hypothesis, we investigated whether CRC cell-derived microvesicles can affect the cell cycle of endothelial cells.
Therefore, in order to experimentally verify the hypothesis that miR-93 is involved in the regulation of both IL-8 and VEGF, we modulated the miR-93 expression in the human glioma cell line U251 by transfecting the cells with pre-miR-93 and antagomiR-93 molecules.
Finally, we experimentally verified the network-driven hypothesis by showing a significant increase in proliferation of endothelial cells treated with the microvesicles.
These hypotheses are experimentally verified or falsified.
But they do sketch a hypothesis which, if experimentally verified, would go a long way towards answering a smaller but still important question - not how consciousness arises, but what kinds of brain activity are necessary to produce consciousness.
If this hypothesis could be experimentally verified, a series of new drug combinations could be proposed based on this assumption.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com