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29, 30 The use of PCR more than doubled the estimated burden of S. pneumoniae associated with meningitis compared with culture alone.
Before adding up the estimated burden of disease from various chemicals, any joint effects of different risks need to be considered.
The estimated burden related to this practice is around 9.18 million disability-adjusted life years (DALYs) between the years 2000 and 2030 [ 13].
However, its importance amongst patients receiving oral antidiabetics may not be as well recognised and the estimated burden resulting from hypoglycaemic episodes in diabetes mellitus type 2 (T2DM) may therefore be underestimated.
For incinerators, cancer incidence "attributable" to exposure before 2001 ("past exposure") was estimated (burden of disease non-modifiable by policy) as it is likely that it will continue to appear until 2050.
While the impact of other viruses has been simultaneously estimated, their impact was not always statistically significant and could be ignored without significantly altering the estimated burden attributed to influenza in an adult population.
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These estimated burdens reflect high regional HIV prevalence rates in pregnant women during the 1990s and lack of interventions to prevent mother-to-child transmission at that time.
A larger sample may also be needed to estimate burden than to estimate prevalence, because burden is not distributed equally among cases: most of it is accounted for by a minority of those with the disorder.
A larger sample may be needed to estimate burden than to estimate prevalence, because burden is not distributed equally among cases: most of it is accounted for by a minority of those with the disorder.
Urban slum and rural disease incidence and clinic utilization are sufficiently disparate in Africa to warrant data from both settings for estimating burden and focusing interventions.
Unfortunately, the majority of pathogens fall within category 3, for which data sources are entirely inadequate to estimate burden.
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