Sentence examples similar to Establishes a function for from inspiring English sources

Using molecular biology approaches, we demonstrate that ectopic expression of META1 and site-directed mutagenesis of selected residues in the predicted META1 cavity do affect secretory processes in Leishmania, thus establishing a function for this poorly characterized protein as well as identifying a functional domain within the molecule.

"It's clear beyond a shadow of a doubt that they've established a function" for PrP, says Neil Cashman, a neuroscientist at the University of British Columbia in Vancouver, Canada.

This finding establishes for the first time a function for the hitherto puzzling CTR, with a plausible central role in RNA transactions.

In summary, our data establishes a novel function for cPMLΔ5&6 in viral infection that involves the immediate early HSV-1 protein ICP0.

The work establishes a new function for this naturally unstructured Hfq domain.

The demonstration that H3K14 deacetylation promotes recruitment of the Clr4 histone methyltransferase establishes a new function for the Sir2 deacetylase in de novo heterochromatin formation.

The results indicate a function for cdc8 in establishing the polarity of the cellular actin cytoskeleton.

Recent publications established a critical function for MYBBP1A as an important regulator of distinct transcription factors, such as the proto-oncogenes MYB and NFκB as well as the tumor suppressor p53, implicated in cell cycle control and carcinogenesis [ 10, 11, 23, 24].

To the best of our knowledge, our analysis is the first to establish a stabilizing function for such elements by a systematic approach.

These data provide insight into a mechanism by which innate immune signals can modify cellular defenses and establish a new function for the NLRP3-inflammasome and caspase-1 in host defense.

Our findings establish a new function for Cdc48/p97 in RAD.