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The addition of an opiate, to attenuate the haemodynamic response, is an established modification of hospital RSI techniques [ 23].
Cells were treated ex vivo with either melphalan (50 μM) or cisplatin (150 μM) for 1 hour, drug removed and the level of ICLs measured with time using the established modification of the single cell gel electrophoresis (comet) assay [ 19].
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We utilized previously established modifications for Asian populations, using waist circumference (WC) cut-off points [ 24].
Once established, modifications to the four letter abbreviations are strongly discouraged in order to maintain clarity, even in cases of renaming or reclassification.
Established modifications to chromatin include methylation of DNA and histones, and further modifications to histones include acetylation, phosphorylation, and ubiquitination, with the N-terminal tail of histone H3 being subjected to a particularly complex set of modifications.
It will be important to determine the functional and temporal relationships among these established modifications in modulating the accumulation of PHF-tau in AD and other age-related neurodegenerative diseases.
6 Takahashi and Yamanaka et al devised an accessible model of cell reprogramming from the differentiated to the induced-pluripotent state, in which somatic to pluripotent states are reverted by re-establishing modification of epigenetic markers.
This government issued two decrees establishing modifications to the national flag.
The departments of Treasury and Housing and Urban Development established loan modification programs for people who fell behind on their mortgages.
We established that modification of the culture condition by lowering pHe from pH 7.4 to pH 6.5 induces cell-cycle arrest in GSLCs as confirmed by the up-regulation of the expression of CDKN1A and G0S2 and the down-regulation of CCNB1, without modification of their stemness properties as seen by the expression of the stemness markers, NANOG, OLIG2 and SOX2,.
New road and airport fragility functions for ash thickness are established through modification of those proposed by Wilson et al. (2017).
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