Due to increased expression of the insulin receptor (InR) and IRS proteins, the responsiveness to insulin generally increases upon adipocyte differentiation [63], [64].
Due to increased expression during PC progression RON may still prove to be an effective therapeutic target.
Thus, removing glucose from the medium does slightly increase biotinylation due to increased expression of BirA, but not AvIsc proteins.
Mitochondria from immature rats also show increased susceptibility to apoptosis; this increased susceptibility might be due to increased expression of pro-apoptotic proteins (Soane et al., 2008).
Initially, increased neo-angiogenesis due to increased expression of the pro-angiogenic factor HIF-1α was also found as a consequence of IDH1 mutation [ 10].
This mimicking recapitulated many features of the BBB in vivo; a dramatic increase in TEER due to increased expression of tight junction proteins [ 15, 19, 32], lowering of passive permeability [ 19] and up-regulation of important nutrient transporters [ 38, 39].
This is partially due to increased expression of ApoE levels and increased mobility of endothelial progenitor cells.
We report that TG2 deficiency results in accelerated and increased adipogenesis in MEFs due to increased expression of adipogenic transcription factors PPARγ and C/EBPα.
Increased GFAP immunoreactivity is believed to occur due to increased expression on existing cells and not due to an increase in the number of astrocytes.
Expression of wild-type human GFP-cortactin (WT) led to a 2-fold increase in motility, presumably due to increased expression of this variant over endogenous (Ctl) levels (Figure 6A).
Indeed, they exhibit a significantly increased anti-angiogenic surveillance, possibly due to increased expression of anti-angiogenic regulators on chromosome 21 [ 57].
