Sentence examples for Direct promoter from inspiring English sources

c-Myc may enhance reprogramming by augmenting transcription of pluripotency inducing factors through direct promoter binding.

Due to a lack of suitable SMARCB1 antibodies for immunoprecipitation, we were unable to perform ChIP experiments to show whether SMARCB1 transactivated CDKN1C by direct promoter binding.

For the first time it is shown here that an Alu can function as a direct promoter for a human gene.

We then validated this prediction by direct promoter analysis using luciferase reporter assays.

The best performing genes from the qualitative analysis (CDO1, DCLK1 and ZSCAN18) were subjected to direct promoter bisulfite sequencing.

We determined a role for NAP1L1 in the regulation of p57 Kipromoterter methylation in BON cells by direct promoter binding of NAP1L1.

By using this new protocol, the production H2O2 was almost doubled compared to the non-modified material when no direct promoters were added to the reaction environment.

Importantly, the observed co-expression of PDGFβ-R and α-SMA further strengthens the identity and presence of activated CAFs, whose role(s) as direct promoters of metastasis, angiogenesis and chemoresistance is increasingly clear [ 14, 15, 46].

CSFs have been implicated as direct promoters of both tumour cell growth and migration (Mueller et al, 1999; Obermuller et al, 2004) and have also been shown to have paracrine as well as autocrine tumour promoting properties as they modulate the tumour stroma and enhance angiogenesis in a squamous skin carcinoma model (Obermuller et al, 2004).

Apart from disrupting genes, IS6110 insertions have also been found to activate gene expression of nearby genes by an outward directed promoter (OP6110) at the 3' end of the insertion element [30], [31], [32].

For example, the outward directed promoter hexamers inside the TIR signals of many IS elements, such as IS1, IS2, and IS5, may activate the expression of the neighboring genes, if the IS elements are inserted appropriately [ 9, 13].