Toxicity-per-cycle data is given only for the first six cycles, in patients on the formal phase II trial, to avoid bias from dose reductions and differing data collection methods (Table 4-wrap>).
Although invitees were told in the study information leaflet that they were part of a pilot project and that their participation would assist "in deciding the best way of implementing the Link-Up Project", they were not aware of the trial hypotheses or randomisation to differing data collection site types, fasting status and reminder letter receipt.
Differing definitions, data collection methods, drug type/regimen and patient populations make comparing rates of hypoglycaemia difficult.
After the four week acclimatization period, M T, L S, and K did not differ for fish from different collection sites or exposed to different acclimatization treatments.
She and her sister grew up studying piano and ballet, and listening to their parents' wildly differing music collections – the Brel, Gainsbourg, Tchaikovsky and Debussy belonged to their mother, while their father was a fan of Deep Purple, the Beatles and the Rolling Stones.
Neither PFS (hazard ratio [HR] of modified to standard, 1.13; 95% confidence interval [CI],.62 to 2.08; P = .70) nor overall survival (OS) (HR modified to standard,.85; 95% CI,.39 to 1.86; P = .68) were found to differ by collection method.
Overall, medicine quality did not differ by collection method, although open surveyors were less likely to obtain oral artemisinin-based monotherapies than MCs.
Nonetheless, starting M T and L S were significantly lower for fish collected from Inlet Stream West (M T : F1,77 = 4.652, P = 0.034; L S : F1,77 = 4.998 P = 0.028), although condition (K) did not differ between collection sites.
Although it might have been possible to measure MMA retrospectively, in cats where stored serum was available, variability in sample collection procedures (e.g. differing times between collection and freezing of samples), time and temperature of storage could have made the results less reliable.
In some cases, sample sizes differed between collections particularly between some samples collected early in the study and those collected more recently.
