Sentence examples for Demyelinating disorder from inspiring English sources
Multiple sclerosis (MS) is an immune mediated demyelinating disorder of the central nervous system (CNS) characterized by inflammatory lesions in the brain and spinal cord that result in varying degrees of neurological impairment.
Acute disseminated encephalomyelitis (ADEM) is a monophasic inflammatory demyelinating disorder that can follow an infectious disease or vaccination.
Autosomal dominant leukodystrophy (ADLD) is an adult onset demyelinating disorder that is caused by duplications of the lamin B1 (LMNB 1) gene.
No opportunistic infections, tuberculosis, lymphomas, other malignancies (other than one incidence of non-melanoma skin cancer), demyelinating disorder or deaths were observed through week 26.
Axonal loss is widely accepted as the major cause of permanent neurological disability in multiple sclerosis (MS), an inflammatory demyelinating disorder of the central nervous system.
Although traditionally viewed as a white matter (WM) demyelinating disorder, MS is characterized by acute and chronic axonal and neuronal loss, as shown for long by pathological and neuroimaging studies [ 1, 2].
However, there is debate about whether treatment with anti-TNFα blockers unmasks preexisting demyelinating disorders such as multiple sclerosis (MS) or induces de novo demyelination of the central nervous system (CNS) and peripheral nervous system.
Stathopoulos, P., Alexopoulos, H. & Dalakas, M. C. Autoimmune antigenic targets at the node of Ranvier in demyelinating disorders.
Demyelinating disorders, such as multiple sclerosis, attack these cells and degrade nerve transmission, especially over long distances.
Multiple sclerosis and acute disseminated encephalomyelitis are demyelinating disorders of the central nervous system that can present initially as an acute focal demyelinating syndrome.
Such insight will be essential in designing new therapeutic strategies to promote remyelination in demyelinating disorders such as multiple sclerosis.
