Sentence examples for Deficient backgrounds from inspiring English sources

In the M2 population, the TGFBR2 sequence in the hMLH1−/− background demonstrated the highest mutation frequency (highest at day 21, 240-fold change) over time compared to other different MMR deficient backgrounds as predicted in EGFP histograms (Fig. 3E).

Moreover, it is suitable for studies concerning bone tissue engineering [31], and for supplying hormonal factors to deficient backgrounds [32].

That study is difficult to compare to our current study since their genetic experiments were performed in germline deficient backgrounds and did not address the role mir-71 has in determining wild type lifespan.

We originally suggested that in telomerase deficient backgrounds this ubiquitous SCE recombination-based mechanism might be used to advantage at telomeres to extend cellular proliferative life [ 11], however more recent work and modeling suggest that T-SCE possess the potential to accelerate cellular senescence, and so may be a contributing factor in premature aging [ 34, 43].

The relatively low frequency of chromatid-type telomere fusion we observed in DNA-PKcs deficient backgrounds, together with the incomplete, transient nature of the tankyrase 1 knockdown and associated DNA-PKcs degradation, likely explain the paucity of telomere-telomere fusion seen here.

These data suggest that mice with Fsp27 deficiency in both wild type and leptin deficient background all have improved glucose disposal rate.

Using Kc cells, we performed a genome wide RNAi screen for regulators of cell number in a sensitized, Pvr deficient background.

Unexpectedly, the loss of RB on an Inha deficient background does not worsen disease progression.

T-lymphocytes have PTH receptors and PTH induces altered responses in a T-cell deficient background [11], [12], [13].

However, to our knowledge, mouse models of AAA have not been applied in either TNF or p55 TNFR deficient background.

In this Mre11-nuclease deficient background, there is also reduced viability of the transformant containing the pRS314dna2K1080E,E675A (nuclease minus, helicase minus).