With regards to the number of databases or screen datasets incorporated, to our knowledge, no published database is comparable to CrossCheck, as even the largest monotype database, such as BioGRID, currently amounts to only 49986 entries, while CrossCheck currently consists of 614,161 entries.
The process simulation used in the GaBi® datasets incorporates process (heat, water and mass) integration and waste treatment technologies.
This shows that, for most normalisation techniques, increasing the number of datasets incorporated in model inference decreases the error when this model is subsequently applied to the test dataset.
Twenty datasets incorporating known E. coli TFBS sequences were created (Table 1).
Nine datasets incorporating known prokaryotic motifs discovered by ChIP methods were also created (Table 2).
Relevant gene expression and clinical data was extracted from ten publicly available datasets incorporating approximately 1,300 samples.
Missing values were computed using multiple imputation with 25 complete datasets incorporating baseline covariates and crash outcomes.
In total, 4,738 samples across 26 datasets incorporating 12 different microarray platforms were utilised to develop the BreastMark system (Table 1).
Across all five tissue-specific datasets, incorporating two different methods of library construction, RXE values for all paralogs were higher than all non-paralogous genes.
The GLOBAL-DEVEL network, unsurprisingly, is highly influenced by expression datasets incorporating developmental-stage-specific exposures (e.g. hormone treatments and the A. thaliana expression atlas [ 20]).
Through an integrated analysis of literature data and internal datasets incorporating both cell line models and human tumors, we identified a RAS pathway signature consisting of 147 genes that is coherently expressed across multiple datasets.
