We chose three multiclass microarray datasets (detailed described in the Datasets section) for our experiments.
For all datasets, details of taxon numbers, positions and models of sequence evolution are listed in Additional file 6.
To this end, we examined expression datasets detailing the relative abundance of a large number of human TFs across 40 normal and cancer cell types.
We also ran all analyses and robustness checks using the Hooghe et al. data, and the results are consistent across these two datasets (details available from the authors).
In Canada with universal health insurance coverage, the health services are provided to all residents; therefore, almost all Canadians are represented by these datasets (details available from the Canada Health Care System website) [ 9].
In all other respects except the ω distribution our set of 100 replicates was generated with the same parameters as the 5-taxon tree datasets detailed in Wong et al. [ 17].
From the datasets detailed in those studies, a subset of 11 overlapping landmarks, observable and with clear homology in both fissipeds and pinnipeds, and identifiable in all the fossils, was selected.
For Dependency Models, BHIT showed its remarkable capabilities in detecting multiple dependencies both in discrete and continuous datasets detailed in Table 2, while no other publicly available tools can handle these data.
This result is further corroborated by the results from stress expression datasets (detailed in a later section), suggesting that these retained duplicates might have contributed to the species-specific stress response in green algae.
We sample the 71 cases from the full set of 466 cases provided by Geisinger (see dataset details in Methods).
The dataset details when and where each individual was born and died, and mirrors the demographics of Geni.com individuals, with 85percentt of profiles originating from Europe and North America.
