Maleszka, R., de Couet, H. G. & Miklos, G. L. G. Data transferability from model organisms to human beings: insights from the functional genomics of the flightless region of Drosophila.
Seventh, Drosophila is indeed facile in terms of experimental manipulation, but it has major drawbacks that impinge upon data transferability (e.g., the lack of DNA methylation toolkit and reproductive division of labour54).
In discussing the implications of Royalactin, the author overlooks the vast trove of data on conditional phenotypes1,2,3,4,5,6,14, the quantitative biological constraints that are manifested during development and the inherent pitfalls in data transferability between different species at particular levels42.
The meta-analyses were carried out concerning the following topics: measurement uncertainties, conflicting results, method uncertainty, lack of data, transferability to environmental conditions, transferability to other nanoparticles, applicability of models, knowledge gaps, sources of uncertainty, and consequences of uncertainty.
Confirmatory evidence (objectivity) was sought by comparison across the transcripts, field notes and with the quantitative data (transferability).
In order to assess whether HapMap SNPs are applicable to other closely related population, Ribas et. al. [ 22] evaluated the HapMap SNP data transferability with CEU as a reference panel in the Spanish population.
However, high synteny of genome existing across eucalypt species has benefited many DNA data deficient eucalypts taxa, thus excellent SSR transferability was witnessed across species (da Silva et al. [2009]; Acuna et al. [2012a]).
To gain deeper quantitative insights into GWAS transferability, we developed a complex trait coalescent-based simulation framework considering effects of polygenicity, causal allele frequency divergence, and heritability.
Similarly, high rates of SSR transferability have been observed in other Rosoideae genera, including Potentilla where 86%94%% transferability between species was reported.
Due to the good SNP transferability rate to FL population, we decided to design high-throughput SNP assay from WD population.
In this study SNP transferability in the strict sense was tested because each of the analysed Vitis species is highly heterozygous and also because for several purposes (e.g. mapping) only heterozygous markers can be used.
