This article reviews the technology, current practices, and data on plaque excision.
Amyloid imaging with [ C]Pittsburgh Compound-B (PiB) provides in vivo data on plaque deposition in those with, or at risk for, Alzheimer's disease (AD).
According to our data calcified plaques show less inflammatory infiltrate, a smaller lipid core, and less neoangiogenesis than other plaques, but with the same incidence of hemorrhage, thrombosis, and surface defects, which define the plaque as histologically complicated [ 10].
Plaque data suggest an inverse relationship with recession; plaque scores lower at recession sites [ 11].
To further investigate whether large plaques can form from multiple small precursor plaques, we analyzed the entire data set of plaques to find those which contained at least two distinct Methoxy-XO4 positive cores within an Aβ antibody positive plaque (≥2 separate Methoxy-XO4 positive particles).
All 24 possible combinations (pairs) of the following 4 pathology SoTs and 6 image endpoints were studied: Pathology data (SoT) (a) Plaque as a percentage of area IHC-stained with 4G8 antibody (b) Bielschowsky silver plaque score (normal/abnormal) (c) Thioflavin S plaque score (normal/abnormal) (d) Overall pathology (normal/abnormal) Normal and abnormal are defined below.
In addition, sST2 levels were associated to patient clinical data and atherosclerotic plaque characteristics.
To date, several studies have been published looking at variability in SUV measurements; however, to date, no studies have looked into differences between PET-CT software packages when carotid atherosclerotic plaque data obtained through the same scanner are analysed.
The data for the plaque assays and RT-PCR assays are compiled in Tables S1 and S2.
Minimum/maximum values are presented for plaque data.
