Sentence examples for DNA targeting from inspiring English sources

Recent advances in DNA targeting allow unprecedented control over gene function and expression.

Applications of recombinases are, however, constrained by the DNA targeting endemic of the recombinase used.

Triplex-forming oligonucleotides (TFOs) are sequence-dependent DNA binders that may be useful for DNA targeting and detection.

TAL effector targeting has merits that are distinct from those of the RNA-based DNA targeting CRISPR/Cas9 system.

The clustered regularly interspaced short palindromic repeat (CRISPR) system has emerged as the revolutionary platform for DNA targeting.

Additionally, unlike other endonucleases, the specific DNA targeting of Cas9 was guided by an engineered guide-RNA by means of base-pair complementarity.

We directly compared the performance of Rnt1p/EU2dT to an RNase H/DNA oligonucleotide (EU2-DNA) targeting the same sequence in total RNA and cell extract (Figure 5E).

Because promoters are the main genomic regions in which T-DNA integration occurred, we analyzed further promoter regions to investigate the involvement of host-DNA asymmetry and T-DNA host-DNA shared microhomologies T-DNA host-DNA-DNA T-DNA host-DNA

Our interest in the 4-methoxypyrrolic natural products has been focused on gaining an understanding of their DNA-targeting properties.

In models for BRCA1- or BRCA2-associated breast cancer, we observed a substantial synergy between the defect in homology-directed DNA repair and sensitivity to DNA-targeting drugs.

Through further advances, these programmable DNA-targeting antimicrobials may help quell the spread of antimicrobial resistance and provide a tool for the manipulation of complex microbial communities.