Sentence examples for DNA gain from inspiring English sources
DNA gain occurs by HGT, a process well-established as a major driver of genetic innovation [ 26, 27].
However, we also observed that PT1, PT2 and PT3 (NL-type) cells shared a combined DNA gain at the EGFR locus and a DNA loss at the PTEN locus, which was not observed in the HD-type of GBM cells (see Additional File 3: Table S3).
An overall significant association of approximately one half of down or up regulated genes with, respectively, DNA gain or loss was established.
Fourteen miRNAs were located within regions of copy number variation common to both SCC and ACs (one associated with DNA loss and 13 associated with DNA gain).
Also, there were cases of inversely regulated genes, 14% down regulated in regions of DNA gain and 9% up regulated in regions of DNA loss.
The mutational equilibrium model [18], on the other hand, suggests that a balance between the DNA loss occurring through the predominance of small deletions over small insertions and the DNA gain obtained through the predominance of large insertions over large deletions, determine the equilibrium of GS. iii.
In vitro delivery of DNA mimics the normal physiological conditions where human DNA gains entry into the cells as complexed with proteins or cell debris from dying cells or immune complexes.
Other available datasets enabled the association of differentially expressed genes with areas of genomic DNA gains and losses.
Recent studies using comparative genomic hybridization of genomic DNA have produced a high resolution map for regions of DNA gains and losses for pancreatic cancer cell lines, including the 6 used in the present study.
Overall, DNA gains were more frequent than losses.
The majority of DNA gains (72%) were on the long arms of chromosomes 1 and 8.
