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However, the Rb protein is believed to be a crucial controller of the transition from G1 into the S of the cell cycle which is regulated by this protein's phosphorylation state [16], [17], [36].
The serine/threonine mammalian target of rapamycin (mTOR) is a critical component of an adaptive system that senses the availability of a variety of nutrients and growth factors in the microenvironment and appears as a crucial controller of metabolic homeostasis.
Among these, p27 Kis1 is well established as a tumor suppressor being a crucial controller of cellular proliferation, also in PCa, hence its significant augmentation along with Bim, another pivotal factor influencing apoptosis is reflected in the analysis of cell cycle.
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Swiss air traffic officials acknowledged today that a collision alarm system in their control network was out of operation and that one of two crucial controllers had taken a break at the time of a midair crash that killed 71 people on Monday night.
The new head of fiction will oversee a huge amount, including BBC films, but Tranter's No 2, Ben Stephenson, will gain more autonomy, receiving a crucial promotion to controller of drama commissioning.
Ground radar, known as Airport Surface Detection Equipment, was crucial, since the controllers had little visibility.
Massagué's team had implicated these cells as crucial surveyors and controllers of cancer metastasis.
In Software-Defined Networks (SDNs) the role of the centralized controller is crucial, and thus it becomes a single point of failure.
In addition, there is crucial need of current controller designs in order to precisely regulate an insertion indexes as well as optimize the energy variation within each converter arm.
For this setup, proper controllers are crucial to achieve the desired performance.
Robust autonomous controllers are crucial in this case to manage the charging operation without violating the grid standard limits.
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