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In vitro drug sensitivity assay revealed that suppression of NDRG2 could sensitize Hela cells to cisplatin.
Our results showed that H6 could sensitize KBV and MCF7/T cells to paclitaxel and vincristine.
We hypothesized that an increase in BIM activity could sensitize CML cells to TKI.
Disruption of those defenses could sensitize bacteria to immune attacks and lead to new anti-infective modalities.
Some studies suggested that antioxidant supplementation could sensitize cancer cells to chemo- or radio-therapy and reduce their side effects by protecting the normal cells [270].
Furthermore, siRNA knockdown of Notch 1 or γ-secretase inhibitor (GIS) treatment that prevents Notch pathway activation could sensitize colon cancer cells to oxaliplatin and prevent chemoresistance [79].
This indicates that CGRP not only contributes to proliferation of CGRP-containing nociceptors, but could sensitize these nociceptors via neurogenic inflammation in humans.
It was proposed that elevated RAMP1 expression could sensitize the trigeminal ganglion of individuals to CGRP actions such as CGRP release and neurogenic inflammation [47].
Previously, we found genistein could sensitize cancer cells to low linear energy transfer (LET) X-rays via inhibiting DNA-PKcs activities.
But nowadays, researches also implied that anthracyclines could sensitize tumor cells to immune cell driven cytotoxicity, like dendritic cells and CD8+ T cell.
In addition, H2O2 killing and human whole blood killing assays proved 21b could sensitize S. aureus to be killed under oxidative stress conditions.
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